If you’re building a dietary supplement brand in 2025, let’s talk about something you should know.
One of the most common label errors I see? Using a serving size that doesn’t match what your product directions actually say. And in 2025, this is still a big reason for warning letters and online listing takedowns.
Let’s clear it up once and for all.
What Does the FDA Really Mean by “Serving Size”?

The serving size on your Supplement Facts panel must reflect the maximum amount of the product recommended per eating occasion.
That’s the key phrase: per eating occasion.
The confusion often comes in when a product says something like “Take 1 capsule, up to 3 times daily.” That means your serving size is 1 capsule, because the maximum per eating occasion is one.
You’re showing what someone will consume in a single use, not across the entire day.
Why the Maximum Dose Matters in 2025
Most supplement brands want to be flexible with their usage instructions. I get it, but FDA has been sending warning letters specifically calling out brands that miscalculate serving size.
Retailers like Amazon are also tightening enforcement. If your serving size and usage directions don’t match, your listing may be removed without warning.
These mismatches raise red flags for the FDA, Amazon, and sometimes even retail partners.
How to Check Your Supplement Serving Size

Step 1: Read your usage instructions.
Underline the highest number of units your directions say someone can take at one time.
Step 2: Look at your Supplement Facts panel.
Your serving size should match the number from step 1. Not close. Not rounded. The same.
Step 3: Double-check your math.
All the nutrient amounts listed must reflect that exact serving size. If you say 3 capsules, your listed values need to represent what’s in all 3, not 1.
It’s a simple fix that makes a big difference.
What Happens if You Get It Wrong
Using the wrong serving size can lead to:
- FDA warning letters
- Amazon delistings
- Import delays
- Relabeling
- Customer complaints
None of that feels good. All of it can be avoided.
Serving Sizes Aren’t a Gray Area

They’re clearly defined by the FDA and easy to get right when you know what to look for.
Make sure your usage instructions match your serving size. Easy peasy.
Need Help Fixing It?
I review supplement panels all the time for brands just like yours. Whether you’re launching for the first time or double-checking before scale, this is one of the quickest, most impactful ways to protect your business.
Let’s make sure your label is shelf-ready.
Happy labeling!
Resources:
Dietary Supplement Labeling Guide: Chapter IV. Nutrition Labeling

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